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You Don’t Have to Age

April 18, 2021 by  
Filed under blog

 Source: New York Times, Oct. 31, 2006 Photo Jeff Miller, U of Wisconsin

I am only 35 months away from hitting the big 80, so I have been thinking about age a lot lately. That’s why I’m pulling from an old blog post of mine, one that hits close to home and that I would like to share with you.

Have you ever wondered what you will look like when you reach age 85? More and more Americans are living that long and longer. Statistics from the Society of Actuaries and the Annuity for the year 2000, shows that a male, aged 65, has a 50% chance of living beyond age 85 and a 25% chance of living beyond age 92. A female, aged 65, has a 50% chance of living beyond age 88 and a 25% chance of living beyond age 94. But what will make the difference for any one of us?

There is some evidence to show that calorie restriction and resveratrol could make the difference between which side of those life expectancy statistics you’re on.

Above you see two rhesus monkeys. The one on the left eats a calorie-restricted diet, while the monkey on the right eats a normal diet. Both monkeys are in their late 20s. Their normal lifespan is 30-40 years. As you can see, they look to be in quite different conditions. Here is how the New York Times made note of their differences:

At 28, getting on for a rhesus monkey, Matthias is losing his hair, lugging a paunch and getting a face full of wrinkles.

Yet in the cage next to his, gleefully hooting at strangers, one of Matthias’s lab mates, Rudy, is the picture of monkey vitality, although he is slightly older. Thin and feisty, Rudy stops grooming his smooth coat just long enough to pirouette toward a proffered piece of fruit.

Tempted with the same treat, Matthias rises wearily and extends a frail hand. “You can really see the difference,” said Dr. Ricki Colman, an associate scientist at the center who cares for the animals.

The scientists believe it’s the restricted calories that made the difference between the condition of the monkeys but have found that resveratrol, a molecular mimic of calorie restriction, may deliver the same benefits without food deprivation. There is more human testing to be done, but researchers themselves became so convinced of this they begun taking resveratrol pills themselves.

How does resveratrol work? Studies have shown that Resveratrol turns old cells into young cells. Old cells typically accumulate extra copies of ribosomal DNA that clog the cell and impair cellular function. Resveratrol reverses this.

I think it may also be important to note that recent studies indicate that resveratrol works best when taken in small amounts. There are varying opinions on how much that actually is, however. From 200mg a day or less to simply drinking a glass of red wine has been suggested. The idea is that more is not better with this compound. Too much can actually block the mechanisms that allow resveratrol to help keep up young.

So, if you want to look good as you age, you can go on a nutritionally smart restricted calorie diet or try resveratrol or a little of both. Also, don’t forget to keep having novel experiences, make and reach for big goals, stay social, and exercise. We all get older every year, but there is no reason to age faster than necessary.

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